Table 3. Self-report incident diabetes at follow-up in relation to hazard ratio (HR) of total knee replacement (TKR) (n = 47,869).
| N | Cases | Person-years | Model 1 | Model 2 | Model 3 | |
|---|---|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | ||||
| Total at follow-up | ||||||
| No diabetes | 44,434 | 1,276 | 434,427 | 1.00 | 1.00 | 1.00 |
| Incident diabetes | 3,435 | 89 | 31,713 | 0.94 (0.76–1.17) | 0.74 (0.59–0.92) | 0.75 (0.60–0.93) |
| Men at follow-up | ||||||
| No diabetes | 18,996 | 223 | 181,104 | 1.00 | 1.00 | 1.00 |
| Incident diabetes | 1,545 | 18 | 14,016 | 1.06 (0.65–1.71) | 0.80 (0.49–1.30) | 0.83 (0.51–1.34) |
| Women at follow-up | ||||||
| No diabetes | 25,438 | 1,053 | 253,323 | 1.00 | 1.00 | 1.00 |
| Incident diabetes | 1,890 | 71 | 17,698 | 0.91 (0.72–1.16) | 0.72 (0.57–0.92) | 0.74 (0.58–0.94) |
HRs were adjusted for the following variables in separate models:
Model 1: age at follow-up (years); year of recruitment (1993–1995, 1995–1998); dialect group (Hokkien, Cantonese), level of education (no formal education, primary school, secondary school or higher).
Model 2: above adding BMI at follow-up (model 2).
Model 3: model 2 adding self-reported histories of physician-diagnosed coronary heart disease or stroke at follow-up, smoking status at follow-up (never, former, or current), numbers of hours per week spent in moderate physical activity, vigorous work, and strenuous sports.