| Cluster 1 |
Enrichment Score: 1.405 |
Calcium-binding domain |
|
|
| INTERPRO |
IPR018247:EF-HAND 1 |
6 |
2.098 |
0.035 |
| INTERPRO |
IPR018249:EF-HAND 2 |
6 |
2.098 |
0.038 |
| INTERPRO |
IPR011992:EF-Hand type |
6 |
2.098 |
0.045 |
| Cluster 2 |
Enrichment Score: 1.372 |
Cysteine-type activity |
|
|
| GOTERM_MF_FAT |
GO:0004198 ~ calcium-dependent cysteine-type endopeptidase activity |
3 |
1.049 |
0.011 |
| GOTERM_MF_FAT |
GO:0008234 ~ cysteine-type peptidase activity |
4 |
1.399 |
0.066 |
| GOTERM_MF_FAT |
GO:0004197 ~ cysteine-type endopeptidase activity |
3 |
1.049 |
0.106 |
| Cluster 3 |
Enrichment Score: 0.897 |
Cytochrome |
|
|
| PIR_SUPERFAMILY |
PIRSF000045:cytochrome P450 CYP2D6 |
3 |
1.049 |
0.013 |
| INTERPRO |
IPR002401:Cytochrome P450, E-class, group I |
3 |
1.049 |
0.068 |
| INTERPRO |
IPR017973:Cytochrome P450, C-terminal region |
3 |
1.049 |
0.080 |
| INTERPRO |
IPR017972:Cytochrome P450, conserved site |
3 |
1.049 |
0.084 |
| SP_PIR_KEYWORDS |
heme |
4 |
1.399 |
0.091 |
| INTERPRO |
IPR001128:Cytochrome P450 |
3 |
1.049 |
0.107 |
| SP_PIR_KEYWORDS |
Monooxygenase |
3 |
1.049 |
0.124 |
| COG_ONTOLOGY |
Secondary metabolites biosynthesis, transport, and catabolism |
3 |
1.049 |
0.148 |
| GOTERM_MF_FAT |
GO:0020037 ~ heme binding |
4 |
1.399 |
0.159 |
| GOTERM_MF_FAT |
GO:0046906 ~ tetrapyrrole binding |
4 |
1.399 |
0.176 |
| GOTERM_MF_FAT |
GO:0009055 ~ electron carrier activity |
4 |
1.399 |
0.301 |
| SP_PIR_KEYWORDS |
iron |
4 |
1.399 |
0.399 |
| GOTERM_MF_FAT |
GO:0005506 ~ iron ion binding |
4 |
1.399 |
0.614 |
| Cluster 4 |
Enrichment Score: 0.860 |
Signaling |
|
|
| UP_SEQ_FEATURE |
signal peptide |
19 |
6.643 |
0.048 |
| SP_PIR_KEYWORDS |
signal |
19 |
6.643 |
0.111 |
| SP_PIR_KEYWORDS |
glycoprotein |
16 |
5.594 |
0.492 |
| Cluster 5 |
Enrichment Score: 0.833 |
Sexual development |
|
|
| GOTERM_BP_FAT |
GO:0045137 ~ development of primary sexual characteristics |
3 |
1.049 |
0.117 |
| GOTERM_BP_FAT |
GO:0003006 ~ reproductive developmental process |
4 |
1.399 |
0.151 |
| GOTERM_BP_FAT |
GO:0007548 ~ sex differentiation |
3 |
1.049 |
0.180 |
| Cluster 6 |
Enrichment Score: 0.760 |
Ion binding |
|
|
| GOTERM_MF_FAT |
GO:0043167 ~ ion binding |
40 |
13.986 |
0.130 |
| GOTERM_MF_FAT |
GO:0046872 ~ metal ion binding |
38 |
13.287 |
0.190 |
| GOTERM_MF_FAT |
GO:0043169 ~ cation binding |
38 |
13.287 |
0.213 |
| Cluster 7 |
Enrichment Score: 0.725 |
Respiratory development |
|
|
| GOTERM_BP_FAT |
GO:0030324 ~ lung development |
3 |
1.049 |
0.145 |
| GOTERM_BP_FAT |
GO:0030323 ~ respiratory tube development |
3 |
1.049 |
0.145 |
| GOTERM_BP_FAT |
GO:0060541 ~ respiratory system development |
3 |
1.049 |
0.150 |
| GOTERM_BP_FAT |
GO:0035295 ~ tube development |
3 |
1.049 |
0.400 |
| Cluster 8 |
Enrichment Score: 0.723 |
Protease activity |
|
|
| GOTERM_MF_FAT |
GO:0004175 ~ endopeptidase activity |
8 |
2.797 |
0.129 |
| GOTERM_MF_FAT |
GO:0070011 ~ peptidase activity, acting on L-amino acid peptides |
9 |
3.147 |
0.190 |
| GOTERM_MF_FAT |
GO:0008233 ~ peptidase activity |
9 |
3.147 |
0.215 |
| GOTERM_BP_FAT |
GO:0006508 ~ proteolysis |
12 |
4.196 |
0.242 |
| Cluster 9 |
Enrichment Score: 0.703 |
Calcium-binding domain |
|
|
| UP_SEQ_FEATURE |
calcium-binding region:2 |
3 |
1.049 |
0.126 |
| INTERPRO |
IPR002048:Calcium-binding EF-hand |
4 |
1.399 |
0.148 |
| UP_SEQ_FEATURE |
calcium-binding region:1 |
3 |
1.049 |
0.157 |
| SMART |
SM00054:EFh |
4 |
1.399 |
0.187 |
| UP_SEQ_FEATURE |
domain:EF-hand 1 |
3 |
1.049 |
0.258 |
| UP_SEQ_FEATURE |
domain:EF-hand 2 |
3 |
1.049 |
0.258 |
| INTERPRO |
IPR018248:EF hand |
3 |
1.049 |
0.333 |
| Cluster 10 |
Enrichment Score: 0.668 |
Embryonic development |
|
|
| GOTERM_BP_FAT |
GO:0001824 ~ blastocyst development |
3 |
1.049 |
0.082 |
| GOTERM_BP_FAT |
GO:0001701 ~ in utero embryonic development |
4 |
1.399 |
0.165 |
| GOTERM_BP_FAT |
GO:0043009 ~ chordate embryonic development |
4 |
1.399 |
0.397 |
| GOTERM_BP_FAT |
GO:0009792 ~ embryonic development ending in birth or egg hatching |
4 |
1.399 |
0.400 |
| Cluster 11 |
Enrichment Score: 0.565 |
Cardiomyopathy |
|
|
| KEGG_PATHWAY |
bta05412:Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
3 |
1.049 |
0.240 |
| KEGG_PATHWAY |
bta05410:Hypertrophic cardiomyopathy (HCM) |
3 |
1.049 |
0.277 |
| KEGG_PATHWAY |
bta05414:Dilated cardiomyopathy |
3 |
1.049 |
0.304 |
| Cluster 12 |
Enrichment Score: 0.519 |
Phosphorylation |
|
|
| GOTERM_MF_FAT |
GO:0004672 ~ protein kinase activity |
9 |
3.147 |
0.213 |
| GOTERM_BP_FAT |
GO:0006468 ~ protein amino acid phosphorylation |
9 |
3.147 |
0.291 |
| GOTERM_BP_FAT |
GO:0016310 ~ phosphorylation |
9 |
3.147 |
0.447 |
