Table. 3. Results of the combination of gentamicin and green tea extract against S. aureus and P. aeruginosa.
| Bacterial | strains | Agent | MIC (μg/mL) | FIC | FICI | Outcome | |
|---|---|---|---|---|---|---|---|
| Alone | Gentamicin + Extract | ||||||
| S. aureus | 1 | gentamicin | > 80 | > 80 | 1 | 2 | Indifference |
| green tea extract | 250 | 250 | 1 | ||||
| S. aureus | 2 | gentamicin | 20 | 10 | 0.5 | 0.75 | Partial synergy |
| green tea extract | 1000 | 250 | 0.25 | ||||
| S. aureus | 3 | gentamicin | > 80 | 80 | 1 | 2 | Indifference |
| green tea extract | > 80 | 500 | 1 | ||||
| S. aureus | 4 | gentamicin | 500 | > 80 | 1 | 2 | Indifference |
| green tea extract | 500 | 500 | 1 | ||||
| S. aureus (ATCC 6538p) | 5 | gentamicin | 0.312 | 0.156 | 0.5 | 0.56 | Partial synergy |
| green tea extract | 500 | 31.25 | 0.06 | ||||
| P. aeruginosa (ATCC 9027) | 1 | gentamicin | 0.312 | 0.156 | 0.5 | 1 | Additive |
| green tea extract | 1000 | 500 | 0.5 | ||||
S. aureus, Staphylococcus aureus; P. aeruginosa, Pseudomonas aeruginosa; MIC, minimum inhibitory concentration; FICI, fraction inhibitory concentration index.