Table. 4. Results of the combination of gentamicin and EGC against S. aureus and P. aeruginosa.
Bacterial | strains | Agent | MIC (μg/mL) | FIC | FICI | Outcome | |
---|---|---|---|---|---|---|---|
Alone | Gentamicin + Extract | ||||||
S. aureus | 1 | gentamicin | > 80 | 20 | 0.25 | 0.75 | Partial synergy |
EGC | 62.5 | 31.25 | 0.5 | ||||
S. aureus | 2 | gentamicin | 20 | 10 | 0.5 | 1.5 | Indifference |
EGC | 125 | 125 | 1 | ||||
S. aureus | 3 | gentamicin | > 80 | 80 | 1 | 1.5 | Indifference |
EGC | 125 | 62.5 | 0.5 | ||||
S. aureus | 4 | gentamicin | > 80 | 80 | 1 | 2 | Indifference |
EGC | 62.5 | 62.5 | 1 | ||||
S. aureus (ATCC 6538p) | 5 | gentamicin | 0.312 | 0.156 | 0.5 | 0.56 | Partial synergy |
EGC | 62.5 | 3.90 | 0.06 | ||||
P. aeruginosa (ATCC 9027) | 1 | gentamicin | 0.312 | 0.312 | 0.5 | 2.5 | Indifference |
EGC | 125 | 250 | 2 |
EGC, epigallocatechin; S. aureus, Staphylococcus aureus; P. aeruginosa, Pseudomonas aeruginosa; MIC, minimum inhibitory concentration; FICI, fraction inhibitory concentration index.