Table. 5. Results of the combination of gentamicin and EGCG against S. aureus and P. aeruginosa.
| Bacterial | strains | Agent | MIC (μg/mL) | FIC | FICI | Outcome | |
|---|---|---|---|---|---|---|---|
| Alone | Gentamicin + Extract | ||||||
| S. aureus | 1 | gentamicin | > 80 | 2.5 | 0.03 | 0.53 | Partial synergy |
| EGCG | 62.5 | 31.25 | 0.5 | ||||
| S. aureus | 2 | gentamicin | 20 | 10 | 0.5 | 0.75 | Partial synergy |
| EGCG | 62.5 | 15.62 | 0.25 | ||||
| S. aureus | 3 | gentamicin | > 80 | 80 | 1 | 2 | Indifference |
| EGCG | 62.5 | 62.5 | 1 | ||||
| S. aureus | 4 | gentamicin | > 80 | 80 | 1 | 2 | Indifference |
| EGCG | 62.5 | 62.5 | 1 | ||||
| S. aureus (ATCC 6538p) | 5 | gentamicin | 0.312 | 0.156 | 0.5 | 1.5 | Indifference |
| EGCG | 125 | 125 | 1 | ||||
| P. aeruginosa (ATCC 9027) | 1 | gentamicin | 0.312 | 0.312 | 0.5 | 1 | Additive |
| EGCG | 250 | 125 | 0.5 | ||||
EGCG, epigallocatechin gallate; S. aureus, Staphylococcus aureus; P. aeruginosa, Pseudomonas aeruginosa; MIC, minimum inhibitory concentration; FICI, fraction inhibitory concentration index.