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. 2016 Sep 21;118(2):160–168. doi: 10.1038/hdy.2016.78

Table 1. Heritability (median posterior distribution and s.d.) using different SNP subsets.

SNP subset No. SNPs Median hG2 S.d. hG2
All autosomal 25 109 276 0.78 0.14
Synonymous 6 175 640 0.68 0.20
Non-synonymous 43 254 0.70 0.19
Tolerated non-synonymousa 31 145 0.70 0.19
Deleterious non-synonymousa 9566 0.78 0.14
Enhancersb 1 294 669 0.67 0.21
Transcription factorsc 1 290 312 0.67 0.21
Potentially regulatoryd 1 707 865 0.72 0.18
a

According to SIFT algorithm implemented in ensembl's variant effect predictor (database v. 79).

b

Obtained from Villar et al. (2015).

c

Using SNPs in TFs obtained from animal transcription factor database (www.bioguo.org/AnimalTFDB/, Zhang et al., 2012).

d

Comprises miRNAs, UTR, upstream, downstream and non-mediated decay transcript variants.