Table 1.
Demographic and Clinical Characteristics
| Case (n=108) | Control (n=108) | p value | |
|---|---|---|---|
| Age, median years (IQR) | 60.3 (55.6–65.5) | 57.9 (53.6–63.1) | 0.04 |
| Female, n (%) | 50 (46.3) | 50 (46.3) | 1 |
| Race/ethnicity, n (%) | 0.46 | ||
| White | 28 (25.9) | 24 (22.2) | |
| Black | 62 (57.4) | 57 (52.8) | |
| Hispanic | 16 (14.8) | 25 (23.1) | |
| Other | 2 (1.9) | 2 (1.9) | |
| Follow Up | |||
| Median follow time, months (IQR) | 32.2 (13.0–50.6) | 102.4 (91.3–121.3) | <0.0001 |
| Dead at last follow up, n (%) | 32 (29.6) | 5 (4.6) | <0.0001 |
| Follow up colonoscopy after index adenoma (controls) | --- | 81 | --- |
| Time to follow up colonoscopy (controls), median yrs | --- | 5.5 | --- |
| Follow up colonoscopy ≥3 years after index adenoma (controls), n (%) | --- | 74 (91.2) | --- |
| CRC Location (cases)* | |||
| Right Colon | 54 (50) | --- | --- |
| Left Colon/Rectum | 54 (50) | --- | --- |
| Summary SEER Stage (cases), n (%) | |||
| Local | 41 (37.96) | --- | --- |
| Regional | 33 (30.56) | --- | --- |
| Distant | 27 (25.00) | --- | |
| Unknown/unstaged | 7 (6.48) | --- | --- |
| Features of Adenoma Included for Analysis | |||
| Mean Size, cm (SD) | 1.18 (0.7) | 1.06 (0.5) | 0.16 |
| Advanced Adenoma§, n (%) | 64 (59.3) | 59 (54.6) | 0.5826 |
*
Right colon=proximal to descending colon;
§
adenoma ≥10mm in size, and/or containing high grade dysplasia, tubulovillous, or villous features; IQR, interquartile range; SEER, Surveillance Epidemiology and End Results