Table 2.

Distribution of molecular marker results for case and control adenomas

	All Adenomas (n=216)			Case Adenomas (n=108)			Control Adenomas (n=108)
Marker	n	Median Score	(IQR)	n	Median Score	(IQR)	N	Median Score	(IQR)	p value**
BCAT percentage score*	213	47.08	(20–70)	107	54.6	(30–90)	106	39.49	(20–60)	<0.001
BCAT intensity score*	213	1.48	(1–2)	107	1.6	(1–2)	106	1.37	(1–2)	0.013
p53 percentage score	214	3.42	(0.00–1.37)	107	5.18	(0.02–2.34)	107	1.66	(0.00–0.74)	0.003
p53 intensity score	204	40.12	(14.12–61.52)	103	39.4	(15.9–59.07)	101	40.86	(6.80–61.60)	0.95
Cox 2 percentage score*	206	22.22	(5–30)	103	27.79	(10–50)	103	16.65	(0–20)	<0.0001
Cox 2 intensity score*	206	0.96	(1–1)	103	1.19	(1–2)	103	0.73	(0–1)	<0.0001
Survivin percentage score*	210	14.86	(0–20)	105	21.1	(0–30)	105	8.62	(0–10)	<0.0001
Survivin intensity score*	210	0.68	(0–1)	105	0.78	(0–1)	105	0.58	(0–1)	0.012
p21 percentage score	208	19.01	(1.11–30.32)	104	24.23	(1.67–41.49)	104	13.8	(0.10–20.43)	0.004
p21 intensity score	208	57.75	(18.67–97.3)	104	63.74	(24.65–99.42)	104	51.76	(14.78–90.77)	0.028
DNAPkcs percentage score	208	71.35	(42.98–99.73)	105	85.75	(91.08–99.98)	103	56.68	(28.39–87.38)	<0.0001
DNAPkcs intensity score	208	141.86	(120.60–166.64)	105	158.61	(139.30–184.80)	103	124.79	(108.50–148.75)	<0.0001
MGMT percentage score	211	5.35	(0.02–1.1)	108	9.16	(0.04–4.84)	103	1.36	(0.00–0.36)	<0.0001
MGMT intensity score	211	36.21	(12.00–58.05)	108	43.22	(14.38–65.02)	103	28.85	(10.45–43.9)	<0.001

^*subjectively measured, no decimals used;

^**comparison case vs. control adenoma; IQR, interquartile range; BCAT, beta catenin; DNAPkcs, DNA dependent protein kinase; MGMT, 0(6)-methylguanine-DNA methyltransferase.