Table 3. Mann-Whitney U test (one-tailed) P values for pairwise comparisons of different Ka/Ks distributions.

	Complex disease	Mendelian disease	All genes
Mendelian disease	1.6 × 10-3
All genes	1.5 × 10-4	7.5 × 10-7
Coding polymorphic genes	3.9 × 10-3	1.79 × 10-1	<1 × 10-17