Total white blood counts in monkeys infected with Harper and India strains of smallpox (a), platelet counts in plasma from infected monkeys (b), infectious viral titers recovered from throat swabs of infected monkeys (c), and skin lesions scores as a function of viral dose (India strain) (d). Lesion scores: 3, >500 lesions; 2, 50-500 lesions; 1, 1-50 lesions.