Fig. 9.

Effects of individual or combined inhibition of DGAT1 and DGAT2 on the incorporation of added oleate or glycerol into TAG. Cells were incubated with glucose, oleate, and glycerol (see text for concentrations). When present, CL was added 2 h before the addition of label, either (A) 1-¹⁴C-oleate or (B) 2-³H-glycerol. The inhibitors (DGAT1-iB to inhibit DGAT1 and DGAT2-iJ to inhibit DGAT2, specifically) were added 30 min before the addition of label. Values are means (± SEM) for three separate experiments. Values that are statistically significantly different from those for control (P < 0.05) are indicated by an asterisk.