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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: AAPS J. 2016 Mar 30;18(4):861–875. doi: 10.1208/s12248-016-9904-3

Fig. 5.

Fig. 5

a Local sensitivity of the improved cellular disposition model with respect to intracellular unconjugated (tubulin) bound drug as an output, b pathway analysis of in vitro cellular disposition model for assessing relative importance of antigen-mediated and diffusion pathways of intracellular drug delivery, and c pathway analysis of in vivo tumor disposition model for assessing relative importance of antigen-mediated and diffusion pathways of intracellular drug delivery