Table 1. Demographic and clinical characteristics of breast cancer survivors who received their initial treatment at our institution (MDA-treated) or elsewhere (OTH-treated).
| Characteristic | No. (%) | p valuea | ||
|---|---|---|---|---|
| Total cohort, n = 5091 | MDA-treated, n = 4534 | OTH-treated, n = 557 | ||
| Age at diagnosis | 0.044 | |||
| 35 years or younger | 270 (5.3) | 238 (5.2) | 32 (5.8) | |
| 36–59 years | 3357 (65.9) | 2967 (65.4) | 390 (70.0) | |
| 60 years or older | 1464 (28.8) | 1329 (29.3) | 135 (24.2) | |
| Mean age at diagnosis (standard deviation) | 53.3 years (11.7 years) | 53.6 years (11.6 years) | 51.1 years (11.7 years) | <0.001 |
| Year of diagnosis | <0.001 | |||
| 1995 or earlier | 75 (1.5) | 0 (0.0) | 75 (13.5) | |
| 1996–2000 | 1508 (29.6) | 1312 (28.9) | 196 (35.2) | |
| 2001–2005 | 2541 (50.0) | 2265 (50.0) | 276 (50.0) | |
| 2006 or later | 967 (19.0) | 957 (21.1) | 10 (1.8) | |
| Race/ethnicity | <0.001 | |||
| White | 3727 (73.2) | 3356 (74.0) | 371 (66.6) | |
| Black | 506 (9.9) | 421 (9.3) | 85 (15.3) | |
| Spanish/Hispanic | 647 (12.7) | 563 (12.4) | 84 (15.1) | |
| Other | 211 (4.1) | 194 (4.3) | 17 (3.1) | |
| Tumor receptor status | <0.001 | |||
| Hormone receptor-positive | 3691 (72.5) | 3300 (72.8) | 391 (70.2) | |
| Triple-negative | 722 (14.2) | 614 (13.5) | 108 (19.4) | |
| HER2-positive | 678 (13.3) | 620 (13.7) | 58 (10.4) | |
| Initial tumor stage | <0.001 | |||
| 0 | 60 (1.2) | 57 (1.3) | 3 (0.5) | |
| I | 2669 (52.4) | 2422 (53.4) | 247 (44.3) | |
| II | 1873 (36.8) | 1660 (36.6) | 213 (38.2) | |
| III | 489 (9.6) | 395 (8.7) | 94 (16.9) | |
| Tumor grade | 0.002 | |||
| I | 402 (7.9) | 359 (7.9) | 43 (7.7) | |
| II | 2426 (47.7) | 2198 (48.5) | 228 (40.9) | |
| III | 2263 (44.5) | 1977 (43.6) | 286 (51.3) | |
| Histologic findings | <0.001 | |||
| Ductal | 4066 (79.9) | 3586 (79.1) | 480 (86.2) | |
| Lobular | 423 (8.3) | 390 (8.6) | 33 (5.9) | |
| Mixed | 315 (6.2) | 304 (6.7) | 11 (2.0) | |
| Other | 287 (5.6) | 254 (5.6) | 33 (5.9) | |
| Received chemotherapy | 3372 (66.2) | 2974 (65.6) | 398 (71.5) | 0.006 |
| Received endocrine therapy | 3710 (72.9) | 3358 (74.1) | 352 (63.2) | <0.001 |
| Surgery | 0.012 | |||
| Lumpectomy | 2585 (50.8) | 2330 (51.4) | 255 (45.8) | |
| Mastectomy | 2506 (49.2) | 2204 (48.6) | 302 (54.2) | |
| Received radiation therapy | 3395 (66.7) | 2990 (65.9) | 405 (72.7) | 0.001 |
a A two-sample t test was used to compare mean age between the groups; Pearson’s chi-square tests were used for all other comparisons.