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. 2017 Jan 13;12(1):e0170081. doi: 10.1371/journal.pone.0170081

Table 2. Survival and recurrence outcomes in breast cancer survivors who received their initial treatment at our institution (MDA-treated) or elsewhere (OTH-treated).

Outcome No. (%)
Total cohort, n = 5091 MDA-treated, n = 4534 OTH-treated, n = 557
Overall survival
 Alive 4583 4189 (92.4) 394 (70.7)
 Dead 508 345 (7.6) 163 (29.3)
 Follow-up period
  Median (range) 8.7 years (5.0–22.3 years) 8.6 years (5.0–16.7 years) 9.0 years (5.0–22.3 years)
  Interquartile range 6.6–11.2 years 6.6–11.1 years 6.8–12.8 years
 Time to eventa
  Median (range) 8.8 years (5.1–19.7 years) 8.7 years (5.1–17.0 years) 8.8 years (5.1–19.7 years)
  Interquartile range 7.0–11.0 years 7.0–10.5 years 7.1–12.0 years
Recurrence-free survival
 Local recurrence 49 (1.0) 26 (0.6) 23 (4.1)
 Local recurrence → death 4 (0.0) 1 (0.0) 3 (0.5)
 Distant recurrence 109 (2.1) 63 (1.4) 46 (8.3)
 Distant recurrence → death 187 (3.7) 98 (2.2) 89 (16.0)
 Local recurrence → distant recurrence 10 (0.2) 2 (0.0) 8 (1.4)
 Local recurrence → distant recurrence → death 19 (0.4) 5 (0.1) 14 (2.5)
 Death only 298 (5.9) 241 (5.3) 57 (10.2)
 Follow-up period
  Median (range) 8.6 years (5.0–20.1 years) 8.6 years (5.0–16.7 years) 8.9 years (5.0–20.1 years)
  Interquartile range 6.6–11.1 years 6.6–11.0 years 6.8–11.6
 Time to event
  Median (range) 7.5 years (5.0–20.1 years) 7.7 years (5.1–16.0 years) 7.2 years (5.0–20.1 years)
  Interquartile range 6.0–7.5 years 6.2–9.7 years 5.6–9.0 years

a Median time to event represents the median time to develop the first event among patients who had an event.