Skip to main content
. Author manuscript; available in PMC: 2018 Jan 11.
Published in final edited form as: Cell Host Microbe. 2016 Dec 29;21(1):84–96. doi: 10.1016/j.chom.2016.12.006

Figure 2. Effects of diet on the fecal microbiota of gnotobiotic mice colonized with CRON and AMER donor communities.

Figure 2

(A) Experimental design used for monotonously-fed AMER-and CRON-colonized mice. Time points (days) for microbiota sampling are shown. (B,C) The first principal coordinates from PCoA plots of unweighted UniFrac (panel B) and weighted UniFrac (panel C) distances show initial community assembly in fecal microbiota of recipient mice. (D, E) PCoA plots of unweighted UniFrac (panel D) and weighted UniFrac (panel E) distances show the effects of experimental treatments on the phylogenetic structures of the various transplanted donor microbiota. Mean positions in PCoA space are shown for fecal samples collected from each mouse 15 to 56 days following gavage of the human donor’s microbiota. Points connected by yellow lines in both panels are from mice colonized by the same AMER donor, and points connected by blue lines are from the same CRON donor. Circle colors in panel D reflect donor DP, and mouse diet treatment in panel E. (F,G) CIV (panel F) and wCIV (panel G) values (mean ± SEM) in fecal microbiota harvested from each mouse 15 to 56 days after gavage.