Table 2.

Association of HIV monoinfection, HCV monoinfection, HIV/HCV coinfection with HOMA-IR adjusted for demographic, lifestyle, and metabolic factors plus markers of microbial translocation, monocyte activation, and inflammation, compared to those with neither infection^¶

Parameter	Fully-adjusted*		Fully-adjusted + I-FABP**		Fully-adjusted + sCD163**		Fully-adjusted + sCD14**		Fully-adjusted + IL-6**
	% Estimate (95%CI)	p-value	% Estimate (95%CI)	p-value	% Estimate (95%CI)	p-value	% Estimate (95%CI)	p-value	% Estimate (95%CI)	p-value
HIV/HCV coinfection	70% (30%, 122%)	<0.001	81% (37%, 138%)	<0.001	42% (4%, 94%)	0.029	75% (34%,129%)	<0.001	70% (30%, 123%)	<0.001
HCV monoinfection	24% (−6%, 65%)	0.125	27% (−4%, 70%)	0.095	9% (−20%, 48%)	0.575	26% (−5%, 68%)	0.112	25% (−6%, 66%)	0.125
HIV monoinfection	18% (−3%, 43%)	0.097	25% (2%, 54%)	0.036	13% (−7%, 38%)	0.228	20% (−1%, 48%)	0.063	18% (−3%, 43%)	0.097

^¶Multiple imputation by the Chained Equation method was used to impute missing outcome values

^*Adjusted for age, gender, race, smoking, alcohol, BMI, waist circumference, and estimated glomerular filtrate rate.

^**Adjusted for age, gender, race, smoking, alcohol, BMI, waist circumference and estimated glomerular filtrate rate and each of the stated biomarkers