Fig. 4.

Receiver operating characteristic (ROC) curves for distinguishing malignant (adenocarcinoma) tissue sites from non-malignant (normal and chronic pancreatitis) tissue sites using PCA parameters from both reflectance and fluorescence data (solid blue line), PCA parameters from only reflectance data (dashed red line), and PCA parameters from only fluorescence data (dashed green line). The ROC curves were generated by applying a threshold to the optical diagnosis probability of adenocarcinoma. The area under the ROC curve was 0.89 for combined reflectance and fluorescence parameters, 0.89 for only reflectance parameters, and 0.86 for only fluorescence parameters.