Table 4.

Multivariable Logistic Regression Model of Factors Affecting RNA Quality Outcome

NameB,D	≤4.5 RIN		≥6.5 RIN		Odds RatioE	95% CI	p-value
	n	% or ValueA	n	% or ValueA
Cause of Death
Anoxia	11	35%	20	65%	-	-	-
Cerebrovascular/Stroke	10	50%	10	50%	0.28	(0.05–1.30)	0.13
Head Trauma	22	71%	9	29%	0.18	(0.04–0.71)	0.02
Other	2	67%	1	33%	0.37	(0.02–4.47)	0.49
C-peptide (ng/mL)	45	1.17 (0.00,16.76)	40	0.59 (0.00,20.55)	0.97	(0.87–1.08)	0.59
Pancreas Lipase (u/L)
Normal	31	47%	35	53%	-	-	-
Elevated or Critical	14	74%	5	26%	0.22	(0.04–0.89)	0.05C
Downtime (minutes)	45	0 (0,75)	40	5 (0,90)	1.02	(0.98–1.05)	0.37
Length of Final Hospitalization Stay (days)
<3	20	67%	10	33%	-	-	-
≥3 to <6	20	59%	14	41%	1.21	(0.35–4.23)	0.77
≥6	5	24%	16	76%	3.21	(0.75–15.24)	0.14
Pancreas Transport Time (hrs)	45	15.0 (±5.3)	40	15.2 (±7.6)	1.01	(0.92–1.10)	0.88
Tissue Storage Time Prior to RNA Extraction (years)	45	1.5 (0.0,6.8)	40	0.5 (0.0,6.1)	0.82	(0.53–1.20)	0.34
Sample Collection Procedures
Original Protocol	36	69%	16	31%	-	-	-
New Protocol	9	27%	24	73%	4.70	(1.32–17.96)	0.02

^ANumber and % are reported for all categorical variables. Use of mean (± 1 SD) or median (min, max) for continuous variables.

^BRefer to tables 1–3 for footnotes on each factor

^CActual value 0.0496

^DInteraction terms storage time by protocol and downtime by hospital stay were not found to be significant (p>0.10) and excluded from the final model.

^ERepresents MLR model-based OR values