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. 2017 Jan 14;23(2):256–264. doi: 10.3748/wjg.v23.i2.256

Figure 1.

Figure 1

Rat liver tissues and their pathological examination. Liver alterations after the rats were sacrificed at different stages during hepatocyte malignant transformation. A: A representative specimen from the control rats with normal diet; B: A representative specimen from the rats with high-fat diet without 2-fluorenyl acetamide (2-FAA); C: A representative specimen from the rats with high-fat diet containing 2-FAA, at early stage; D: A representative specimen from the rats with high-fat diet containing 2-FAA, at interim stage; and E: A representative specimen from the rats with high-fat diet containing 2-FAA, at later stage. The liver sections were examined with hematoxylin and eosin staining and then divided into the control (A1), fatty liver (B1), degeneration (C1), precancerous (D1), and cancerous (E1) groups; A1-E1: The original magnification of the corresponding rat liver sections was × 200.