Table 5.
Diagnostic performances in the identification of G2-3 and stage III-IV pancreatic neuroendocrine neoplasms
| Feature |
Diagnostic performance |
||||
| Se | Sp | PPV | NPV | ||
| Grade 2-3 | Ill defined margins | 54.2 (33.2-73.8) | 90.3 (73.1-97.5) | 81.2 (53.7-95) | 71.7 (54.9-84.4) |
| Vascular infiltration | 29.2 (13.4-51.2) | 96.7 (81.5-99.8) | 87.5 (46.7-99.3) | 63.8 (48.4-76.9) | |
| Liver metastases | 25 (10.6-47) | 96.7 (81.5-99.8) | 85.7 (42-99.2) | 62.5 (47.3-75.7) | |
| Heterogeneous enhancement | 66.7 (44.7-83.6) | 71 (51.7-85.1) | 64 (42.6-81.3) | 73.3 (53.8-87) | |
| Size > 17.5 mm | 91.7 (71.5-98.5) | 61.3 (42.3-77.6) | 64.7 (46.5-79.7) | 90.5 (68.2-98.3) | |
| Size > 20 mm | 79.2 (57.3-92.1) | 60.9 (38.8-79.5) | 67.8 (47.6-83.4) | 73.6 (48.6-52.4) | |
| ADC < 1.21 × 10-3 mm2/s | 70.8 (48.7-86.6) | 64.5 (45.4-80.2) | 60.7 (40.7-77.9) | 74.1 (53.4-88.1) | |
| Stage III-IV | Ill defined margins | 57.7 (37.2-76) | 96 (77.7-99.8) | 93.7 (67.7-99.7) | 68.6 (50.6-82.6) |
| ADC < 1.28 × 10-3 mm2/s | 80.7 (60-92.7) | 64 (42.6-81.3) | 70 (50.4-84.6) | 76.2 (52.4-90.9) | |
Diagnostic performances are expressed as percentages (95%CI). AUC: Area under the curve; Se: Sensitivity; Sp: Specificity; PPV: Positive predictive value; NPV: Negative predictive value.