Table 2.
Comparison of age, gender and cytokine concentrations between severe and mild SFTS patientsa
| Characteristic | Mild patients (n = 36) | Severe patients (n = 14) | p Value |
|---|---|---|---|
| Sex, male, n (%) | 13 (36.1) | 4 (28.6) | 0.613 |
| Age, year | 59.5 (49.3–65.0) | 67 (62.0–73.5) | 0.003 |
| TNF-α | 1.2 (0.7–1.6) | 1.3 (0.5–4.0) | 0.314 |
| G-CSF | 6.9 (5.3–10.6) | 20.1 (11.7–49.1) | 0.001 |
| IFN-γ | 8.8 (3.9–25.1) | 54.3 (6.2–90.4) | 0.005 |
| IFN-α | 11.0 (5.3–18.8) | 26.9 (14.3–138.3) | 0.001 |
| MIP-1α | 12.1 (2.5–30.7) | 56.4 (20.6–222.0) | 0.001 |
| IL-6 | 18.3 (7.9–45.8) | 121.2 (47.5–272.4) | 0.001 |
| MCP-1 | 141.7 (85.4–339.9) | 227.8 (118.6–1185.4) | 0.115 |
| IL-10 | 1188.7 (87.7–2436.2) | 3917.0 (106.9–11025.9) | 0.210 |
| IP-10 | 2178.0 (1260.8–3715.6) | 5385.2 (3362.3–8394.3) | 0.003 |
| RANTES | 4855.4 (3070.1–7739.9) | 4195.5 (2728.6–6199.0) | 0.612 |
Unit: pg/ml; aValues are listed as median range unless otherwise noted