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. 2017 Jan 13;14:2. doi: 10.1186/s12977-016-0325-2

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Change in frequency of HIV integration sites following passaging of cell lines infected with replication-competent HIV. The frequency of unique integration sites per 150,000 cells is shown following passaging of the U1 (green), ACH2 (blue) and J1.1 (red) cell lines. Linear regression was used to determine if the change was statistically significant