Table 3. Genetics and omics data resources either from individuals with ASD or containing data relevant to the study of ASD.a.
| URL | Resourcea | Data type category | Data type | Notes |
|---|---|---|---|---|
| mss.ng | MSSNG | Genetic/Genomic | Phenotypic, genomic (whole genome sequencing of blood DNA) | 10,000 participants. However, data from only 3,000 probands is currently available. |
| gene.sfari.org | Simons Foundation Autism Research Initiative Gene (SFARI Gene) | Gene Catalogue | Animal Model, Protein Interaction (PIN), Gene Scoring, CNV | An up-to-date, manually annotated reference set of ASD-linked genes. |
| projects.tcag.ca/autism | Autism Chromosome Rearrangement Database (ACRD) | Gene Catalogue | Genomic structural variation data—CNVs | A curated catalogue of structural variation related to ASD extracted from publicly available literature and unpublished data. |
| autismkb.cbi.pku.edu.cn/index.php | Autism Knowledgebase (AutismKB) | Gene Catalogue | A collection of genes and variations associated with ASD with annotations | – |
| ncbi.nlm.nih.gov/guide/sitemap/ | National Center for Biotechnology Information (NCBI) | Genetics, omics | A collection of multiple resources—omics and sequencing data | – |
| ebi.ac.uk/services/all | European Molecular Biology Laboratory (EMBL-EBI) | Genetics, omics | A collection of multiple resources—omics and sequencing data | – |
| uniprot.org | Universal Protein Resource (UniProt) | Protein sequences | Protein sequences and their annotations | Can be found among EMBL-EBI resources. 91 (reviewed) and 346 (unreviewed) protein records associated with ASD. |
| ebi.ac.uk/ega | The European Genome-phenome Archive (EGA) | Omics—Functional genomics | Interaction of genotype and phenotype (including data from UK10K project) | Can be found among EMBL-EBI resources. |
| thebiogrid.org | Biological General Repository for Interaction Datasets (BioGRID) | Omics | Genetic and protein interaction data | Resource that archives and disseminates genetic and protein interaction data. |
| gpmdb.thegpm.org/index.html | Global Proteome Machine Database (GPM DB) | Omics—Proteomics | Proteomics data from tandem mass spectrometry | Open-source system for analyzing, storing, and validating proteomics information derived from tandem mass spectrometry. |
| peptideatlas.org | PeptideAtlas | Omics—Proteomics | Peptide sequences, mapping— proteome information/data | A collection of peptides identified in a large set of tandem mass spectrometry proteomics experiments. |
| ddbj.nig.ac.jp/index-e.html | DNA DataBank of Japan (DDBJ) | DNA and RNA sequences | DNA and RNA sequences | Annotated collection of all publicly available nucleotide sequences and their translated amino acid sequences. |
| chr7.org | The Chromosome 7 Annotation Project | DNA sequences | DNA sequence and annotation of the entire human chromosome 7 | 84 cases. |
| mirbase.org | miRBase: the microRNA database | miRNA sequences | miRNA sequences and annotation | – |
| gbrowse.csbio.unc.edu/cgi-bin/gb2/gbrowse/slep | Sullivan Lab Evidence Project (SLEP) | Genetics, omics | A collection of genes and variations associated with ASD with annotations | Findings from genome wide linkage (GWL), genome wide association (GWA), and microarray (MA) studies for ASD. |
Notes.
a
The resources listed in this table contain data either from individuals with ASD or data relevant to ASD research that is collected from non-affected individuals (e.g., from individuals with certain genetic profiles or syndromes related to ASD research).