Fig. 6.
Intercalation of N6-BPDE A adduct in the Dpo4 active site (BP-1), blocking dNTP incorporation. (A) The N6-BPDE-dA:dTTP ternary complex and the surrounding base pairs are shown as ball-and-stick models. (B) Looking down the DNA helical axis, two layers of base pairs and the BPDE adduct are shown. The figures are cited from Ling et al. Proc. Natl. Acad. Sci. U S A, 101 (2004) 2265-2269 [64].Copyright (2004) National Academy of Sciences, U.S.A