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. Author manuscript; available in PMC: 2017 Mar 9.
Published in final edited form as: Science. 2016 Aug 4;353(6304):1129–1132. doi: 10.1126/science.aah6157

Figure 2. Protective efficacy of the ZIKV PIV vaccine.

Figure 2

PIV vaccinated and sham control rhesus monkeys (N=8/group) were challenged by the s.c route with 106 VP (103 PFU) ZIKV-BR or ZIKV-PR. Each group contained 6 female and 2 male animals. Viral loads are shown in (A) plasma, (B) urine, (C) CSF, (D) colorectal secretions, and (E) cervicovaginal secretions. Viral loads were determined on days 0, 1, 2, 3, 4, 5, 6, 7 for the plasma samples (A) and on days 0, 3, 7 for the other samples (B–E). Data is shown for all 8 animals in each panel, except for the 6 females for cervicovaginal secretions in (E). P-value reflects Fisher’s exact test.