Table 3.

Annual change of metabolic indicators after one-year intervention.

		N	Baseline	12 months	Annual decline	p
Lnhs-CRP	P + GM	270	0.05 ± 1.07	0.28 ± 1.04	−0.24 ± 0.95	<0.001
	P + HM	268	0.03 ± 1.17	0.24 ± 1.17	−0.15 ± 0.96	0.011
	DS + GM	277	0.02 ± 1.11	0.15 ± 1.04	−0.15 ± 0.79	0.002
	DS + HM	271	0.05 ± 1.16	0.07 ± 1.1	0 ± 0.98	0.999
TC	P + GM	270	4.44 ± 0.87	4.59 ± 0.91	−0.15 ± 0.73	0.001
	P + HM	268	4.42 ± 0.83	4.55 ± 0.85	−0.14 ± 0.73	0.002
	DS + GM	277	4.52 ± 0.88	4.58 ± 0.88	−0.06 ± 0.67	0.151
	DS + HM	271	4.5 ± 0.88	4.67 ± 0.91	−0.17 ± 0.67	<0.001
TG	P + GM	268	1.16 ± 1	1.76 ± 1.31	−0.14 ± 0.91	0.011
	P + HM	267	1.64 ± 1.2	1.57 ± 1.17	0.04 ± 0.75	0.372
	DS + GM	277	1.57 ± 1.04	1.41 ± 0.88	0.16 ± 0.82	0.001
	DS + HM	270	1.55 ± 1.03	1.33 ± 0.9	0.22 ± 0.93	<0.001
HDL-c	P + GM	270	1.31 ± 0.29	1.29 ± 0.24	−0.02 ± 0.21	0.204
	P + HM	268	1.31 ± 0.28	1.32 ± 0.27	0.01 ± 0.23	0.677
	DS + GM	277	1.35 ± 0.26	1.32 ± 0.25	−0.03 ± 0.23	0.042
	DS + HM	271	1.32 ± 0.26	1.36 ± 0.29	0.05 ± 0.25	0.001
LDL-c	P + GM	270	2.91 ± 0.73	3.07 ± 0.85	−0.03 ± 0.68	0.523
	P + HM	268	2.88 ± 0.82	2.98 ± 0.88	0.03 ± 0.77	0.475
	DS + GM	277	2.97 ± 0.78	3.15 ± 0.89	−0.01 ± 0.64	0.881
	DS + HM	271	2.96 ± 0.8	3.23 ± 0.92	−0.1 ± 0.68	0.017
HbA1C%	P + GM	271	5.68 ± 0.68	5.59 ± 0.8	0.24 ± 0.49	<0.001
	P + HM	270	5.63 ± 0.66	5.52 ± 0.77	0.29 ± 0.7	<0.001
	DS + GM	278	5.64 ± 0.69	5.49 ± 0.6	0.32 ± 0.65	<0.001
	DS + HM	272	5.56 ± 0.69	5.49 ± 0.62	0.31 ± 0.55	<0.001
LnLEP	P + GM	268	3.15 ± 0.83	3.13 ± 0.85	−0.02 ± 0.47	0.55
	P + HM	269	3.13 ± 0.94	3.16 ± 0.85	0.03 ± 0.41	0.298
	DS + GM	275	3.16 ± 0.84	3.12 ± 0.85	0.08 ± 0.44	0.003
	DS + HM	271	3.16 ± 0.92	2.99 ± 0.92	0.16 ± 0.4	<0.001
LnINS	P + GM	271	2.32 ± 0.51	2.48 ± 0.67	−0.16 ± 0.66	<0.001
	P + HM	265	2.36 ± 0.49	2.33 ± 0.61	0.04 ± 0.58	0.259
	DS + GM	277	2.34 ± 0.5	2.18 ± 0.59	0.16 ± 0.55	<0.001
	DS + HM	271	2.45 ± 0.52	2.16 ± 0.63	0.29 ± 0.62	<0.001
GLU	P + GM	270	5.03 ± 1.01	5.27 ± 1.5	−0.16 ± 0.94	0.006
	P + HM	268	4.95 ± 1.22	5.05 ± 1.24	−0.06 ± 1.05	0.388
	DS + GM	277	5.02 ± 1.25	4.97 ± 1.12	0.16 ± 0.82	0.001
	DS + HM	271	4.94 ± 1.07	4.93 ± 0.99	0.03 ± 0.84	0.583
HOMAIR	P + GM	268	2.39 ± 1.73	3.59 ± 3.75	−0.96 ± 3.67	<0.001
	P + HM	265	2.3 ± 1.81	2.86 ± 2.7	0.64 ± 2.24	0.435
	DS + GM	275	2.48 ± 2.35	2.38 ± 2.15	0.32 ± 2.16	0.013
	DS + HM	270	2.36 ± 2.23	2.35 ± 2.17	0.64 ± 2.24	<0.001
HOMAIS	P + GM	268	0.03 ± 0.02	0.02 ± 0.01	−0.0022 ± 0.01	0.008
	P + HM	269	0.03 ± 0.02	0.02 ± 0.02	0.002 ± 0.02	0.037
	DS + GM	275	0.03 ± 0.02	0.03 ± 0.02	0.0049 ± 0.02	<0.001
	DS + HM	271	0.03 ± 0.02	0.03 ± 0.02	0.0085 ± 0.02	<0.001
LnTNF	P + GM	268	3 ± 0.98	3.15 ± 0.83	−0.14 ± 0.73	0.001
	P + HM	269	2.99 ± 1.04	3.01 ± 0.99	−0.04 ± 0.8	0.406
	DS + GM	275	2.93 ± 1.04	3.02 ± 0.98	−0.16 ± 0.82	0.001
	DS + HM	271	2.97 ± 0.95	3.03 ± 0.92	−0.12 ± 0.75	0.006
FFA	P + GM	271	0.47 ± 0.22	0.5 ± 0.26	0.02 ± 0.32	0.215
	P + HM	269	0.48 ± 0.19	0.51 ± 0.3	0 ± 0.33	0.901
	DS + GM	276	0.48 ± 0.21	0.58 ± 0.27	−0.04 ± 0.34	0.071
	DS + HM	269	0.45 ± 0.21	0.56 ± 0.31	0 ± 0.36	0.966
LnADI	P + GM	268	7.71 ± 0.63	7.66 ± 0.8	0.01 ± 0.55	0.794
	P + HM	269	7.73 ± 0.66	7.75 ± 0.71	0.03 ± 0.46	0.22
	DS + GM	275	7.71 ± 0.67	7.74 ± 0.69	0.06 ± 0.46	0.044
	DS + HM	270	7.75 ± 0.77	7.77 ± 0.75	0.03 ± 0.48	0.378

Note. P: placebo; DS: dietary supplements; GM: general management, H: health management.

DS ∗ HM: cross function of dietary supplements and health management.