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. 2017 Jan 14;25:4. doi: 10.1186/s13049-016-0344-y

Table 2.

Grading of anaphylaxis according to severity of clinical symptoms. Mueller 1966

Grade Signs and Symptoms
1 Slight general reaction Generalized urticaria, itching, malaise and anxiety
2 General reaction Any of the above plus two or more of following: generalized edema; constriction in chest; wheezing; abdominal pain; nausea and vomiting; and dizziness
3 Severe general reaction Any of the above plus two or more of following: dyspnea; dysphagia; hoarseness or thickened speech; confusion; and feeling of impending disaster
4 Shock reaction Any of the above plus two or more of following: cyanosis; fall in blood pressure; collapse incontinence; and unconsciousness