Table 4.
The number and percentages of intrasplenic and hepatic tumor formation after intrasplenic injection of HCT116 stable cell lines (1×106 cells each) for 8 weeks
| Modified HCT116 stable cell line | Number of mice | Tumor formationa | |
|---|---|---|---|
| Intrasplenic | Liver | ||
| Vectro | 8 | 6 (75.0) | 6 (75.0) |
| ΔSOCS | 8 | 6 (75.0) | 6 (75.0) |
| WT ASB3 | 8 | 4 (50.0) | 2 (25.0)* |
| G135E | 8 | 7 (87.5) | 8 (100) |
| K339I | 8 | 7 (87.5) | 8 (100) |
| G135E/K339I | 8 | 8 (100) | 8 (100) |
* P < 0.05 compared with other groups (Students’ t test)
a The data are presented as the number of mice with tumors followed by percentage in parentheses