Skip to main content
. Author manuscript; available in PMC: 2017 Jan 15.
Published in final edited form as: Epilepsia. 2015 Dec 9;57(1):151–161. doi: 10.1111/epi.13264

Table 1.

Patient preoperative epilepsy syndrome, PMG characteristics, surgery description, and seizure control outcome

Pt Age, sex Age onset Preop seizure type PMG type and associated imaging findings Epilepsy syndrome Surgery performed Engel
1 3 month, F Birth Focal dyscognitive Multifocal left PMG of frontal pole, convexity and frontal and parietal opercula with transmantle cortical dysplasia and hemimegalencephaly Not available Left hemispherectomy Ia
2 1 year, F Birth ES, focal motor Diffuse left PMG with hemimegalencephaly, pachygyria and subependymal heterotopia Focal refractory with ES, symptomatic of MCD Left functional hemispherectomy Ia
3 9 year, M 6 year Focal motor and dyscognitive, SGTCS, SE, atypical absences, and ESES Bilateral temporal occipital polymicrogyria, bilateral parietal and occipital while matter volume loss and thinning of the posterior corpus callosum ESES Right occipital seizure foci resection Ia
4 34 year, M 26 year Focal ± dyscognitive, motor or SGTCS Right occipital polymicrogyria extending from occipital pole to calcarine sulcus and to posteromedial aspect of occipital horn of lateral ventricle Focal refractory, symptomatic of MCD Right occipital seizure foci resection Ia
5 30 year, F 11 year Focal ± dyscognitive, motor or SGTCS Focal right perisylvian polymicrogyria with involvement of the frontal, parietal and temporal lobes Not available 1. Right frontal seizure foci resection Ic
2. VNS
6 38 year, M 26 year Focal dyscognitive ± SGTCS Right temporal lobe polymicrogyria with cortical dysplasia Focal refractory, symptomatic of MCD Right frontoparietal and temporal seizure foci resection Ic
7 36 year, F Child hood Focal dyscognitive with aphasia and motor symptoms ± SGTCS Bilateral perisylvian polymicrogyria with left closed-lip schizencephaly Focal refractory, symptomatic of MCD Left frontotemporal seizure foci resection IIc
8 4 month, M 4 month Focal motor ± SGTCS Focal right frontal polymicrogyria involving operculum, anterior insula, orbital gyri, reduced white matter volume Focal refractory, symptomatic of MCD 1. Right frontal seizure foci resection IIIa
2. Right functional hemispherectomy
9 10 year, M 5 year Focal sensory and motor ± SGTCS Bilateral occipital lobe polymicrogyria with left parietal gross architectural distortion likely from in utero insult Focal refractory, symptomatic of MCD Left functional hemispherectomy IIIa
10 44 year, F 18 year Focal dyscognitive with aphasia ± SGTCS Left greater than right bilateral posterior perisylvian polymicrogyria extending to parietal operculum Focal refractory, symptomatic of MCD Right anterior temporal, inferior frontal and parietal seizure foci resection IIIa
11 2 year, M 2 month ES, focal motor Focal right perisylvian PMG and hemimegalencephaly Focal refractory with ES, symptomatic of MCD Right functional hemispherectomy IVb
12 16 year, M 3.5 year Focal motor ± dyscognitive, ±SGTCS Focal left perisylvian polymicrogyria with left hippocampal atrophy and nodular heterotopia of the occipital horn Focal refractory, symptomatic of MCD Left superior temporal, peri-insula, and parietal seizure foci resection IVb

PMG, polymicrogyria; FU, follow-up; SGTCS, secondary generalized tonic–clonic seizures; ES, epileptic spasm; SE, status epilepticus; ESES, electrical status epilepticus during sleep; MCD, malformation of cortical development; VNS, vagus nerve stimulator.