Table 3.
Correlation of the predominant histologic subtype with pathologic stage and survival
| Group | Total | VPI | N0 | N1 | N2 | Ia | Ib | IIa | IIb | IIIa | 5-year OS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Low grade | 25 | 0 | 25 | 0 | 0 | 25 | 0 | 0 | 0 | 0 | –* |
| AIS | 6 | 0 | 6 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | |
| MIA | 19 | 0 | 19 | 0 | 0 | 19 | 0 | 0 | 0 | 0 | |
| Intermediate grade | 72 | 16 | 54 | 11 | 7 | 42 | 14 | 6 | 2 | 8 | 70.1% |
| Lepidic | 9 | 3 | 4 | 3 | 2 | 3 | 1 | 3 | 0 | 2 | |
| Acinar | 38 | 8 | 30 | 5 | 3 | 25 | 8 | 2 | 0 | 3 | |
| Papillary | 25 | 5 | 20 | 3 | 2 | 14 | 5 | 1 | 2 | 3 | |
| High grade | 18 | 8 | 8 | 5 | 5 | 4 | 4 | 5 | 0 | 5 | 33.0% |
| Solid | 9 | 5 | 4 | 2 | 3 | 1 | 3 | 2 | 0 | 3 | |
| Micropapillary | 2 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | |
| Mucinous | 7 | 2 | 3 | 2 | 2 | 3 | 0 | 2 | 0 | 2 |
Notes:
*
All data are censored. –, Not applicable, as more than half the number of patients were still alive.
Abbreviations: AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; VPI, visceral pleural invasion; OS, overall survival.