Table 2.
Fasting levels of gastrointestinal, pancreatic, and adipose-derived hormones as well as non-esterified fatty acids in healthy weight controls and obese participants at baseline
| Variable | Non-obese group baseline | Obese group baseline | p value* |
|---|---|---|---|
| C-peptide | 304.6 (234.2–417.5) | 442.6 (261.1–475.3) | 0.10 |
| Ghrelin | 470.4 (380.0–632.5) | 240.3 (212.4–310.1) | <0.001 |
| GIP | 211.8 (177.9–236.3) | 140.2 (88.24–205.2) | 0.013 |
| GLP-1 | 332.7 (311.0–367.5) | 338.9 (314.6–363.5) | 0.84 |
| Glucagon | 89.86 (69.58–145.4) | 106.4 (82.63–179.9) | 0.29 |
| Insulin | 113.7 (90.38–171.8) | 239.8 (132.1–383.6) | 0.024 |
| NEFA | 0.60 (0.51–0.77) | 0.71 (0.49–0.82) | 0.43 |
| Leptin | 687.7 (476.7–1308.0) | 1251.0 (1096.0–2312.0) | 0.036 |
| PAI-1 | 1390.0 (1243.0–1437.0) | 1311.0 (1188.0–1323.0) | 0.17 |
| Resistin | 2010.0 (1589.0–2442.0) | 1230 (1018.0–1831.0) | 0.02 |
Data are reported as median (IQR [25th, 75th percentile]). All values are pg/mL except for NEFA, which is shown as mmol/L
*As determined through unpaired Mann-Whitney U test