Table 2.
Cytokine | No TB recurrence | TB recurrence | Unadjusted Odds Ratio (95%CI) | p-value | ||
---|---|---|---|---|---|---|
N | Median (IQR) | N | Median (IQR) | |||
Monocytes (CD14) | ||||||
Antigen: BCG | ||||||
IL-1β | 37 | 0.96 (0.00 – 2.86) | 12 | 1.46 (0.20 – 7.51) | 1.30 (1.09 – 1.55) | 0.0033 |
IL-12 | 36 | 0.01 (0.00 – 0.51) | 9 | 0.08 (0.00 – 0.34) | 0.40 (0.01 – 11.15) | 0.5901 |
IP10 | 36 | 0.13 (0.00 – 1.14) | 9 | 0.00 (0.00 – 1.34) | 1.53 (0.84 – 2.77) | 0.1640 |
TNF-α | 36 | 1.19 (0.00 – 3.78) | 9 | 1.43 (0.38 – 5.41) | 1.06 (0.78 – 1.44) | 0.7162 |
Antigen: LPS | ||||||
IL-1β | 34 | 21.03 (0.00 – 45.51) | 11 | 0.92 (0.00 – 9.28) | 0.94 (0.89 – 1.00) | 0.0462 |
IL-12 | 33 | 1.85 (0.00 – 7.28) | 9 | 3.08 (1.31 – 7.69) | 0.98 (0.85 – 1.13) | 0.8143 |
IP10 | 33 | 0.00 (0.00 – 1.15) | 9 | 0.18 (0.00 – 2.86) | 0.94 (0.84 – 1.05) | 0.2807 |
TNF-α | 33 | 57.44 (23.10 – 73.02) | 9 | 41.80 (20.95 – 61.51) | 0.95 (0.91 – 1.00) | 0.0316 |
Antigen: HKLM | ||||||
IL-1β | 38 | 45.45 (23.93 – 70.23) | 11 | 25.11 (4.44 – 52.85) | 0.96 (0.92 – 1.00) | 0.0564 |
IL-12 | 37 | 4.81 (0.00 – 8.60) | 9 | 7.14 (4.51 – 7.75) | 1.07 (0.96 – 1.18) | 0.2294 |
IP10 | 37 | 0.52 (0.00 – 1.92) | 9 | 2.13 (0.44 – 2.70) | 0.95 (0.86 – 1.04) | 0.2768 |
TNF-α | 37 | 62.30 (28.50 – 74.55) | 9 | 59.60 (43.94 – 71.30) | 1.00 (0.95 – 1.05) | 0.9469 |
Antigen: CL075 | ||||||
IL-1β | 36 | 51.16 (32.04 – 73.55) | 11 | 10.05 (1.25 – 62.00) | 0.95 (0.91 – 0.99) | 0.0243 |
IL-12 | 35 | 6.42 (2.02 – 15.30) | 9 | 11.29 (9.76 – 18.65) | 1.02 (0.96 – 1.08) | 0.5811 |
IP10 | 35 | 0.09 (0.00 – 1.88) | 9 | 0.54 (0.00 – 1.54) | 1.61 (0.80 – 3.24) | 0.1815 |
TNF-α | 35 | 62.88 (46.20 – 76.72) | 9 | 62.71 (24.45 – 77.10) | 0.99 (0.94 – 1.03) | 0.4948 |
Antigen: LAMMS | ||||||
IL-1β | 16 | 34.81 (28.60 – 56.89) | 5 | 12.50 (0.00 – 17.21) | N/A | |
IL-12 | 15 | 1.19 (0.33 – 1.42) | 2 | 1.40 (0.95 – 1.85) | N/A | |
IP10 | 15 | 0.00 (0.00 – 0.75) | 2 | 0.08 (0.00 – 0.16) | N/A | |
TNF-α | 15 | 40.83 (28.90 – 52.18) | 2 | 43.49 (34.22 – 52.75) | N/A | |
Antigen: TDB | ||||||
IL-1β | 12 | 19.05 (8.97 – 33.42) | 5 | 0.00 (0.00 – 6.33) | N/A | |
IL-12 | 11 | 4.61 (1.96 – 8.65) | 2 | 11.04 (9.17 – 12.90) | N/A | |
IP10 | 11 | 0.00 (0.00 – 0.83) | 2 | 0.21 (0.00 – 0.42) | N/A | |
TNF-α | 11 | 71.22 (52.90 – 76.01) | 2 | 77.64 (73.92 – 81.35) | N/A |