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. 2016 Sep 29;83(2):247–254. doi: 10.1111/bcp.13119

Figure 2.

Figure 2

Illustration of the relative expected changes in clearance (CL) volume of distribution (V) and elimination half‐life with weight (based on allometric principles) and age for the one‐compartment intravenous bolus model. The standard value for weight here is set to 70 kg, so CL and V take the value 1