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. 2016 Jun 2;7(1):106–115. doi: 10.1016/j.apsb.2016.05.002

Table 1.

Antiproliferative activity of MitoHCAsa.

Compd. IC50 (μmol/L)
HepG2
L02
WI38
24 h 48 h 24 h 48 h 24 h 48 h
MitoCA 11.22±0.40 5.40±0.32 105.42±2.16 59.82±5.77 126.50±6.28 66.31±2.16
Mitop-CoA 26.80±1.53 15.33±0.91 185.75±6.39 80.57±6.32 270.45±8.05 112.57±3.87
MitoFA 10.42±0.37 6.49±0.28 89.73±3.47 50.72±4.49 98.63±2.18 53.52±1.71
MitoCaA 9.19±0.25 5.96±0.21 118.68±0.93 66.83±3.49 123.57±6.92 70.57±2.15
CaA 200.89±3.88 92.97±1.35 402.95±18.87 156.14±8.83 280.89±9.47 198.39±7.78
ButylTPP 25.35±1.02 12.81±0.87 120.58±9.97 71.42±6.64 178.67±3.73 88.51±3.95
a

Values represent mean±SEM from at least three independent experiments.