Table 1.
Compd. | IC50 (μmol/L) |
|||||
---|---|---|---|---|---|---|
HepG2 |
L02 |
WI38 |
||||
24 h | 48 h | 24 h | 48 h | 24 h | 48 h | |
MitoCA | 11.22±0.40 | 5.40±0.32 | 105.42±2.16 | 59.82±5.77 | 126.50±6.28 | 66.31±2.16 |
Mitop-CoA | 26.80±1.53 | 15.33±0.91 | 185.75±6.39 | 80.57±6.32 | 270.45±8.05 | 112.57±3.87 |
MitoFA | 10.42±0.37 | 6.49±0.28 | 89.73±3.47 | 50.72±4.49 | 98.63±2.18 | 53.52±1.71 |
MitoCaA | 9.19±0.25 | 5.96±0.21 | 118.68±0.93 | 66.83±3.49 | 123.57±6.92 | 70.57±2.15 |
CaA | 200.89±3.88 | 92.97±1.35 | 402.95±18.87 | 156.14±8.83 | 280.89±9.47 | 198.39±7.78 |
ButylTPP | 25.35±1.02 | 12.81±0.87 | 120.58±9.97 | 71.42±6.64 | 178.67±3.73 | 88.51±3.95 |
Values represent mean±SEM from at least three independent experiments.