Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic structures of PI3K and PTEN, and the related lipid reactions they catalyze. PI3K phosphorylates PIP2 at 3-OH to generate PIP3. As a counterpart of PI3K, PTEN dephosphorylates PIP3 to produce PIP2. PIP2, phosphatidylinositol 4,5-bisphosphate; PIP3, phosphatidylinositol 3,4,5-trisphosphate.
