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. 2017 Jan 3;3(1):e000371. doi: 10.1136/rmdopen-2016-000371

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Relative treatment effects concerning efficacy endpoints in patients with inadequate response to methotrexate for triple therapy versus TNFi–methotrexate at 3 months, 6 months, 1 year and 2 years. ACR70/50/20, American College of Rheumatology 70%/50%/20% response criteria; CrI, credible interval; CRP, C-reactive protein; DAS28, Disease Activity Score including 28-joint count; ESR, erythrocyte sedimentation rate; EULAR, European League Against Rheumatism; FEM, fixed-effects model; LDA, low disease activity; MTX, methotrexate; REM, random-effects model; TNFi, tumour necrosis factor inhibitor. *ACR70 at 6 months was a prespecified primary endpoint.