Figure 3. ABCA7 deficiency blocks CD1d trafficking.

Co-localization by confocal microscopy of CD1d, Caveolin-1, and LAMP-1 on peritoneal macrophages harvested from WT and Abca7^−/− mice (representative images). Frequency of co-localization of CD1d with LAMP-1 quantified from images from 200 cells (bar graph). Data are expressed as mean ± SEM. *p < 0.05, by unpaired, two-tailed Student’s t-test.