. 2016 Nov 30;8(1):118–123. doi: 10.1021/acsmedchemlett.6b00438

Table 3. Rat PK Profiles of Compounds 11 and 17.

compd	t_1/2 (h)^a	AUC (ng·h/mL)^a	Cl (mL/min/kg)^a	Vss (L/kg)^a
11	0.9	386	43.5	1.9
17	1.1	450	36.8	1.6

Mean values (n = 2) in Wistar rat after an administration of 1 mg/kg i.v. Parameters calculated from plasma samples: t_1/2 = half-life, Cl = clearance, AUC = area under the curve, Vss = volume of distribution at steady state.