Scheme 2.
Synthesis of hydrazides 3a–c. Reagents and conditions: (i) CH3I, NaHCO3, DMF, rt, 46 h; (ii) N2H4.H2O, EtOH, reflux, 2–3 h; (iii) (Boc)2O, NaOH, dioxane/H2O, overnight.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.