Table II.
Proportion of days without heartburn and mean severity of heartburn during the 4-week treatment period (full analysis set).
| Measure | Median* | Q1, Q3* | P† |
|---|---|---|---|
| Proportion of days without heartburn | |||
| Placebo, n = 278 | 7.40 | 0.00, 39.30 | |
| Vonoprazan 10 mg, n = 278 | 10.30 | 0.00, 55.60 | 0.2310 |
| Vonoprazan 20 mg, n = 271 | 12.00 | 0.00, 57.10 | 0.0504 |
| Mean severity of heartburn | |||
| Placebo, n = 278 | 1.070 | 0.520, 1.950 | |
| Vonoprazan 10 mg, n = 278 | 0.990 | 0.360, 1.730 | 0.0440 |
| Vonoprazan 20 mg, n = 271 | 0.960 | 0.320, 1.700 | 0.0139 |
Q1 = quartile 1; Q3 = quartile 3.
Values are presented as %.
Wilcoxon rank-sum test calculated on the median.