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Syntheses of 4-bromo-3-methoxybenzoyl chloride (5c). Conditions: a) Br2, EtOH/HOAc, 30 min, room temperature, 52%, b) MeOH/H2SO4, MeOH, 16 h, reflux, 94%, c) Me2SO4, K2CO3, acetone, 3 h, reflux, quant., d) MeI, K2CO3, DMF, 16 h, room temperature, 83%, e) NaOH, H2O, MeOH, 6 h, room temperature, 66%, f) SOCl2, DMF (cat.), 2 h, reflux, not isolated.
