Table 5.

Items to include when reporting predictive models in biomedical research: discussion section.

Item number	Topic	Checklist item
10	Clinical implications	Report the clinical implications derived from the obtained predictive performance. For example, report the dollar amount that could be saved with better prediction. How many patients could benefit from a care model leveraging the model prediction? And to what extent?
11	Limitations of the model	Discuss the following potential limitations: • Assumed input and output data format • Potential pitfalls in interpreting the modela • Potential bias of the data used in modeling • Generalizability of the data
12	Unexpected results during the experiments	Report unexpected signs of coefficients, indicating collinearity or complex interaction between predictor variablesa

^aDesirable but not mandatory items.