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In vivo therapy of B16-F1 melanoma-bearing mice with 111In-NOTA–MNT-MSH (♦), using (A) 2.6, (B) 5.2, and (C) 10.4 MBq/mice, 111In with the same activity (▲), NOTA–MNT-MSH with the same concentration (◊), or saline (■).
Note: *P<0.05 compared to control groups, according to the one-way ANOVA test.
Abbreviations: ANOVA, analysis of variance; MNT, modular nanotransporter; MSH, α-melanocyte-stimulation hormone.
