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. 2016 Jul 12;7(32):50883–50894. doi: 10.18632/oncotarget.10550

Figure 6. pSer229-KDR is highly expressed in invasive pituitary adenomas and associated with poor prognosis.

Figure 6

A. Representative images of pSer229-KDR staining of a tissue microarray, including low pSer229-KDR level in normal pituitary tissue (left panel), moderate pSer229-KDR level in noninvasive pituitary adenoma (middle panel) and high pSer229 KDR level in invasive pituitary adenoma (right panel). Insets show 200× magnifications of the low-power images, scale bar, 50μm. B. Mean H-scores of pSer229-KDR expression in patients in remission and patients with persistent or recurrent disease. ***P<0.001 versus patients in remission. (ANOVA, followed by Newman–Keuls test). C: Significant differences in recurrence-free survival according to pSer229-KDR expression status in 48 patients after surgical removal of prolactin pituitary adenomas. *P<0.05, by the log-rank test.