Table 1. Morphometric analysis.
Cell line | Stress fibers per cell | N/C ratio |
---|---|---|
C-33A | 3 ± 1 | 0.6 |
SiHa | 13 ± 3 | 0.28 |
CaSki | 20 ± 4 | 0.26 |
Morphometric evaluation of two structural cell parameters - number of stress fibers and nucleus/cytoplasm ratio - in three different carcinoma cell lines that express different levels of HPV and E7 DNA: null (C-33A), low (SiHa) or high (CaSki). Of note, significant differences were appreciated between HPV16-null cells and cells with a different number of copies of HPV16 DNA, which show a higher content of polymeric actin stress fibers and also display a larger cytoplasm.