Table 1. Characteristics of the study patients.
| Pt # | Primary disease | Age at time of WBRT | Number of brain lesions | Volume of tumor analyzed (cc) | Time between WBRT and prior surgery or SRS brain treatment | OS from WBRT (months) | Use of Pla, Mem or Neither |
|---|---|---|---|---|---|---|---|
| 1 | Breast | 34 | 1 | 1.73 | Sx: 4 weeks | 20.5 | Pla |
| 2 | Breast | 53 | 4 | 0.78 | N/A | 33.6 | Pla |
| 3 | Lung | 71 | 2 | 0.62 | Sx: 6 weeks RS: 4 weeks |
23.4 | Neither |
| 4 | Breast | 51 | 1 | 1.58 | Sx: 6 weeks RS: 4 weeks |
18.6 | Mem |
| 5 | Colon | 66 | 4 | 0.48 | RS: 4 weeks | 4.0 | Mem |
| 6 | Lung | 65 | >10 | 0.94 | N/A | 5.6 | Mem |
| 7 | Lung | 66 | 4 | 13.06 | N/A | 10.9 | Mem |
| 8 | Melanoma | 65 | 3 | 0.53 | RS: 5 weeks | 4.9 | Mem |
| 9 | Thryoid | 57 | 2 | 1.78 | RS: 59 weeks | 21 | Neither |
| 10 | Lung | 67 | 6 | 0.60 | N/A | 7.2 | Plac |
| 11 | Lung | 44 | 1 | 3.70 | RS: 2 weeks | 0 | Mem |
| 12 | Lung | 78 | >10 | 0.62 | N/A | 5.9 | Plac |
| 13 | Lung | 63 | 2 | 1.37 | Sx: 5 weeks RS: 2 weeks |
28.5 | Mem |
| 14 | Breast | 57 | 2 | 0.65 | RS: 44 weeks | 8.6 | Plac |
WBRT: Whole brain radiotherapy; Sx: Surgery; RS: Radiosurgery; N/A: no surgery or RS; OS: Overall Survival; Pla: Placebo; Mem: Memantine