Table 1. Patients and clinicopathologic factors.

	Training set						Validation set						P*
Factors	Nr0 (n = 701)	Nr1 (n = 441)	Nr2 (n = 484)	Nr3 (n = 477)	Total (n = 2103)	P	Nr0 (n = 157)	Nr1 (n = 115)	Nr2 (n = 109)	Nr3 (n = 91)	Total (n = 472)	P
Gender						0.172						0.248	0.051
Male	501	308	361	333	1503		103	75	71	67	316
Female	200	133	123	144	600		54	40	38	24	156
Age (years)						0.067						0.131	0.059
≥ 60	308	213	209	194	924		73	57	48	52	230
< 60	393	228	272	286	1179		84	58	61	39	242
Tumor location						0.152						0.245	0.112
Upper third	175	104	128	117	524		39	20	25	19	103
Middle third	155	96	96	119	466		38	39	29	22	128
Lower third	357	232	253	230	1072		77	55	53	46	231
≥ 2/3 stomach	14	9	7	11	41		3	1	2	4	10
Macroscopic type						< 0.001						< 0.001	0.069
Borrmann 0–II	395	284	280	225	1184		85	83	59	17	244
Borrmann III– IV	306	157	204	252	919		72	32	50	74	228
Tumor differentiation						< 0.001						< 0.001	0.141
Well/Moderately	138	124	96	56	414		30	25	16	8	79
Poorly	563	317	388	421	1689		127	90	93	83	393
Lymphovascular invasion						0.008						0.003	0.083
Negative	437	292	305	275	1311		90	82	60	42	274
Positive	264	147	179	202	792		67	33	49	49	198
Perineural invasion						0.004						< 0.001	0.054
Negative	560	374	377	368	1679		121	91	69	67	358
Positive	141	67	107	109	424		36	14	40	24	114
Adjuvant chemotherapy						0.087						0.271	0.090
Present	254	181	195	207	837		47	45	44	32	168
Absent/Unclear	447	260	299	270	1266		110	70	65	59	304
Tumor size						< 0.001						< 0.001	0.102
≤ 4.5 cm	234	191	178	99	702		51	54	49	17	171
4.5-7.5 cm	330	188	230	241	989		71	49	43	33	196
≥ 7.5 cm	137	62	73	140	412		35	12	17	41	105
Retrieved lymph nodes						0.901						0.900	0.121
≥ 15	499	323	348	342	1512		119	87	84	66	356
< 15	202	118	136	135	591		38	28	25	25	116
T Stage						< 0.001						< 0.001	0.097
T1	42	52	27	6	127		13	17	3	6	39
T2	81	74	60	28	243		22	29	13	2	66
T3	57	54	41	19	171		10	7	7	6	30
T4a	435	229	309	331	1304		91	57	79	63	290
T4b	86	32	47	93	258		21	5	7	14	47
N Stage						< 0.001						< 0.001	0.194
N0	701	0	0	0	701		157	0	0	0	157
N1	0	316	68	21	405		0	75	16	15	106
N2	0	119	216	84	419		0	26	46	3	75
N3a	0	6	184	215	405		0	11	43	35	89
N3b	0	0	16	157	173		0	3	4	38	45
TNM Stage						< 0.001						< 0.001	0.066
IA	290	0	0	0	290		51	0	0	0	51
IB	129	50	11	2	192		35	10	7	2	54
IIA	101	64	22	3	190		25	10	3	2	40
IIB	92	47	36	12	187		25	9	8	4	46
IIIA	82	171	79	37	369		20	66	6	11	103
IIIB	7	92	167	75	341		1	17	48	12	78
IIIC	0	17	169	348	534		0	3	37	60	100