Table 2. Multivariate Cox regression analyses of the overall survival stratified by HKLC criteria.

	OR(%95 CI)	P
Within HKLC criteria
Therapy (surgery vs. TACE)	0.5 (0.4, 0.6)	<0.001*
Sex (male vs. female)	1.8 (1.1, 2.8)	0.013*
Tumor size, cm (> 5 vs. ≤ 5)	2.0 (1.5, 2.6)	<0.001*
Tumor thrombus (with vs. without)	1.7 (1.0, 2.7)	0.031*
Outside HKLC criteria
Therapy (surgery vs. TACE)	0.6 (0.4, 0.8)	0.001*
AFP, ng/mL (> 20 vs. ≤ 20)	1.6 (1.0, 2.5)	0.048*
Tumor location (more than one vs. one lobe)	1.6 (1.1, 2.4)	0.013*

^*Significant difference.

Abbreviations: OR: odds ratio; CI: confidence interval; ALT: alanine aminotransferase; GGT, gamma-glutamyl transferase; AFP, Alpha-fetoprotein; TACE, transcatheter arterial chemoembolization;