Table 4. Stratified analysis of factors affecting the correlation between tumor size and overall survival.
| Tumor size | No. | Crude OR (95% CI), P | Model I& | Model II& | |
|---|---|---|---|---|---|
| Tumor thrombus | |||||
| Without | ≤ 5 | 430 | Ref. | Ref. | Ref. |
| > 5 | 325 | 1.7 (1.4, 2.0) | 1.6 (1.4, 1.9) | 1.6 (1.3, 1.9) | |
| With | ≤ 5 | 32 | 1.6 (1.0, 2.6) | 1.6 (1.0, 2.4) | 1.5 (1.0, 2.4) |
| > 5 | 154 | 1.7 (1.4, 2.1) | 1.5 (1.1, 2.0) | 1.4 (1.1, 1.9) | |
| P for interaction | 0.048* | 0.044* | 0.041* | ||
| Tumor number | |||||
| ≤ 3 | ≤ 5 | 428 | Ref. | Ref. | Ref. |
| > 5 | 396 | 1.6 (1.4, 1.9) | 1.6 (1.3, 1.9) | 1.5 (1.3, 1.8) | |
| > 3 | ≤ 5 | 34 | 0.9 (0.6, 1.4) | 0.8 (0.5, 1.3) | 0.9 (0.7, 1.3) |
| > 5 | 83 | 1.9 (1.5, 2.6) | 1.8 (1.4, 2.4) | 1.8 (1.3, 2.3) | |
| P for interaction | 0.223 | 0.227 | 0.258 | ||
*
Significant difference.
Abbreviations: OR: odds ratio; CI: confidence interval
Crude: without adjustment.
Model I: with adjustment of age, sex, alanine aminotransferase; gamma-glutamyl transferase; alpha-fetoprotein and total bilirubin.
Model II: with adjustment of age, sex, alanine aminotransferase; gamma-glutamyl transferase; alpha-fetoprotein, total bilirubin, tumor capsule, location and differentiation.