Figure 2. The correlations of cell line responses to individual drugs from CCLE, GDSC and CTRP.

A. CCLE and GDSC correlations. Pearson correlation (r) coefficients of adjusted AUC_IC50 calculated by this study (blue bars) were matched to the similar analyses performed by Haibe-Kains et al. [5] (red bars, unadjusted AUC, Spearman correlation (ρ)), and Stransky et al. [6] (green bars, unadjusted AUC, r). B. CCLE and CTRP correlations (r, adjusted AUC_IC50). C. CTRP and GDSC correlations (drugs are subdivided into kinase inhibitors, other targeted therapies, and cytotoxic chemotherapies; r, adjusted AUC_IC50). Horizontal dashed line shows a threshold for moderate correlation (> 0.5).